Table 2. DSX targets with consistent DSX regulation across strains.
Gene | Chr. | Sex Bias | Regulatory Mode | DSX Occupancya | DSX Occupancyb |
---|---|---|---|---|---|
CG8539 | 3L | Female | Activator | 0 | 0 |
Cpr72Ea | 3L | Female | Female specific activator | 0 | 0 |
Mp20 | 2R | Female | Female specific activator | 0 | 1 |
CG31522 | 3R | Female | Female specific activator | 1 | 0 |
trpl | 2R | Female | Male specific repressor | 0 | 0 |
CG3759 | 2L | Female | Male specific repressor | 1 | 0 |
Yp2 | X | Female | Male specific repressor | 1 | 1 |
Fmo-2 | 2R | Female | Male specific repressor | 1 | 1 |
Yp3 | X | Female | Opposing effects | 0 | 1 |
Yp1 | X | Female | Opposing effects | 1 | 1 |
rost | 2L | Female | Opposing effects/ | 1 | 1 |
Male specific repressor | |||||
CG15012 | 3L | Male | Female specific repressor | 0 | 0 |
mav | 4 | Male | Female specific repressor | 0 | 0 |
CG12158 | 2R | Male | Female specific repressor | 0 | 0 |
Cyp4d21 | 2L | Male | Female specific repressor | 0 | 0 |
CG31145 | 3R | Male | Female specific repressor | 1 | 0 |
CG18547 | 3R | Male | Female specific repressor | 1 | 0 |
Cyp313a1 | 3R | Male | Opposing effects | 0 | 0 |
Genes with patterns of sex-differential expression in wild-type, dsxD pseudo male, and dsx null comparisons, and the same regulatory mode in both Canton S and Berlin strains (FDR < 0.10). Sex bias, the direction of sex-differential expression: Female (Female-biased) or Male (Male-biased); Regulatory mode, the seven types of DSX regulation; DSX occupancy.
DSXM and DSXF ChIP-seq in S2 cells and DSXM and DSXF Dam-ID in female ovaries, and male and female fat body (Clough et al. 2014; Table S1).
DSXF Dam-ID in adult females (Luo et al. 2011; Table S1). Bold indicates validated DSX targets.