Table 6. Amplified genes that presented overexpression and deleted genes that presented decreased expression in Oncomine datasets.
| Event | Region | Genes |
|---|---|---|
| Amp/Overexp | 4q11-q12 | LRRC66, SGCB, SPATA18, SCFD2, CHIC2, PDGFRA, KDR |
| Amp/Overexp | 7p21.1-p15.3 | TWIST1, FERD3L, TWISTNB, TMEM196, MACC1, ITGB8, SP8, SP4, DNAH11, CDCA7L, RAPGEF5, IL6, FAM126A, KLHL7, NUPL2, GPNMB, C7orf30, IGF2BP3, TRA2A, CCDC126, STK31 |
| Amp/Overexp | 7p12.2-p11.2 | VWC2, FIGNL1, GRB10, SEC61G, EGFR, LANCL2, SEPT14, ZNF713, GBAS, PSPH, CCT6A, SUMF2, PHKG1, CHCHD2 |
| Amp/Overexp | 7q31.2 | CAV2, CAV1, CAPZA2 |
| Amp/Overexp | 12q13.2-q13.3 | OR6C1, OR6C68, OR6C4, OR10P1, ITGA7, BLOC1S1, GDF11, SARNP, DNAJC14, WIBG, CDK2, PA2G4, FAM62A, MYL6, SMARCC2, ANKRD52, CS |
| Amp/Overexp | 12q14.3-q15 | CAND1, DYRK2 |
| Del/LOexp | 9p22.1-p21.3 | SLC24A2, MLLT3, KIAA1797, PTPLAD2, IFNB1, IFNW1, IFNA21, IFNA4, IFNA7, IFNA17, IFNA14, IFNA5, IFNA6, IFNA13, IFNA8, IFNA1, MTAP, CDKN2A, DMRTA1, ELAVL2 |
| Del/LOexp | 10q23.2-q23.31 | ATAD1, PTEN |
Amp, amplification in GBM samples; Overexp, overexpression in Oncomine samples; Del, deletion in GBM samples; LOexp, loss of expression in Oncomine samples.