Figure 2.

H1-3XFLAG is globally enriched throughout the N. crassa genome. Normalized read coverage is shown for all 1000 bp windows across N. crassa Linkage Group VII for anti-FLAG ChIP-seq experiments performed with a WT negative control strain (no FLAG protein) and the hH1-3xflag-Hph+ strain (two replicates for each strain are shown). Normalized read coverage is also plotted for an anti-H3K9me3 ChIP-seq experiment performed with the WT. Each spot depicts the read count for a single 1000 bp window normalized to the median enrichment obtained for mitochondrial DNA windows. ChIP-seq; Chromatin-immunoprecipitation combined with sequencing; WT, wild-type.