TABLE IV.
Adjusted Odds Ratios (ORs) and 95% Confidence Intervals (CIs) for 5 Subgroups with Increasing Levels of SVM-Generated Risk Scores Trained on the different sets of “Prior” images
| “Prior” screening | Sub-group | P and N cases a | Adjusted OR | 95% CI | P-value b |
|---|---|---|---|---|---|
| 1 | 1 | 17 – 50 | 1.00 | Baseline | 0.009 |
| 2 | 18 – 49 | 1.08 | [0.50, 2.34] | ||
| 3 | 34 – 33 | 3.03 | [1.46, 6.29] | ||
| 4 | 37 – 30 | 3.63 | [1.75, 7.54] | ||
| 5 | 53 – 14 | 11.1 | [4.97, 24.9] | ||
| 2 | 1 | 17 – 50 | 1.00 | Baseline | 0.018 |
| 2 | 19 – 48 | 1.16 | [0.54, 2.50] | ||
| 3 | 39 – 28 | 4.10 | [1.97, 8.53] | ||
| 4 | 36 – 31 | 3.42 | [1.65, 7.09] | ||
| 5 | 48 – 19 | 7.43 | [3.46, 16.0] | ||
| 3 | 1 | 23 – 47 | 1.00 | Baseline | 0.037 |
| 2 | 19 – 48 | 0.76 | [0.36, 1.58] | ||
| 3 | 33 – 38 | 1.86 | [0.93, 3.72] | ||
| 4 | 34 – 33 | 1.97 | [0.98, 3.95] | ||
| 5 | 50 – 17 | 5.63 | [2.67, 11.9] |
a
Number of P (cancer) and N (cancer free) cases in the corresponding subgroup of cases.
b
P-value to analyze whether the slope of the regression trend line between the risk scores and the adjusted ORs is significantly different from zero.