Table 1.
Sham | OVX-V | OVX-Cromolyn | |
---|---|---|---|
Body weight (g) | 274 ± 9 | 293 ± 7* | 267 ± 10 |
Left ventricle/tibial length (mg/mm) | 12.3 ± 0.5 | 12.4 ± 0.3 | 12.4 ± 0.5 |
Heart rate (bpm) | 283 ± 10 | 275 ± 9 | 288 ± 19 |
Left ventricle mass | 0.624 ± 0.05 | 0.818 ± 0.07* | 0.721 ± 0.03 |
Relative wall thickness | 0.49 ± 0.04 | 0.68 ± 0.05* | 0.56 ± 0.02 |
Left ventricular end systolic dimension (cm) | 0.26 ± 0.02 | 0.31 ± 0.01 | 0.32 ± 0.02 |
Left ventricular end diastolic dimension (cm) | 0.59 ± 0.04 | 0.62 ± 0.01 | 0.63 ± 0.01 |
Fractional shortening (%) | 56.1 ± 2.1 | 51.6 ± 2.6 | 48.7 ± 2.3 |
E-wave deceleration time time (s) | 0.046 ± 0.003 | 0.048 ± 0.002 | 0.052 ± 0.003 |
Emax (cm/s) | 52.9 ± 3.5 | 58.3 ± 1.7 | 56.6 ± 2.5 |
Amax (cm/s) | 37.0 ± 2.2 | 41.2 ± 2.9 | 39.8 ± 2.4 |
E/A | 1.44 ± 0.07 | 1.46 ± 0.14 | 1.46 ± 0.11 |
Myocardial performance index | 0.22 ± 0.02 | 0.33 ± 0.03* | 0.29 ± 0.02 |
V vehicle; OVX ovariectomized; Emax maximum early transmittal filling velocity; Amax maximum late transmitral filling velocity; E/A early-to-late transmitral filling ratio; MPI myocardial performance index. Data are expressed as mean ± SEM.
P<0.05 vs. Sham.