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. Author manuscript; available in PMC: 2017 Oct 28.
Published in final edited form as: J Control Release. 2016 Jan 8;240:312–322. doi: 10.1016/j.jconrel.2016.01.004

Fig. 7.

Fig. 7

(a) Proposed RONS sensing mechanism of RSPN-P13. (b) Representative PA spectra of RSPN-P13 in the absence and presence of ROS. [RSPN-P13] = 5 μg/mL, [RONS] = 5 μM. (c) PA/ultrasound overlaid images of saline-treated (i) and zymosan-treated (ii) regions in the thigh of living mice (n = 3). RSPN-P13 (3 μg in 50 μL) was intramuscularly injected into the thigh 20 min after zymosan treatment. Reproduced from ref. 109.