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. 2016 Jul 6;36(27):7246–7252. doi: 10.1523/JNEUROSCI.0607-16.2016

Figure 3.

Figure 3.

Lack of light-evoked IPSCs in TRN neurons at age P15 or older. All results were obtained from PV-ChR2 mice. Whole-cell recordings were performed, and the holding potential was at 0 mV, the reversal potential of ChR2 currents. The light power was 1.3 mW for all the experiments presented here. A, Lack of light-evoked IPSCs in a TRN neuron at P16. Light pulses were applied either centered at (circle 2, left) or 0.4 mm away (circles 1 and 3) from the recorded cell. Results of five consecutive trials at each spot are shown on the right. B, Lack of light-evoked IPSCs in a TRN neuron at P62. C, Light-evoked IPSCs and the blockade by gabazine in a TRN neuron at P12. The average peak amplitude of light-evoked IPSCs at P11–P13 was 77 ± 17 pA (n = 9 cells).