Table 2.
Vitamin D related molecules in Pleural effusion
| Parameter | IE | ME | CHFE | P Value | Exudate | Transud. | P Value | CIE | NCIE | P Value | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 25OH Vitamin D (ng/mL) | Serum | 12 (5, 84) | 18.4 (6.9, 41) | 10,4 (3, 39.6) | 0,001 | 12.8 (5, 84) | 10.6 (3, 39,6) | 0,019 | 11.85 (9.2, 16.2) | 13.5 (7.6, 22.4) | 0.731 |
| Pleura | 16 (1, 63) | 17 (5.5, 47) | 12.2 (1, 30.5 | 0,016 | 15 (1, 63) | 12 (1, 25) | 0,048 | 16 (9.65, 20.65) | 15 (7.75, 25.32) | 0.551 | |
| 1,25 (OH)2 Vitamin D (pg/mL) | Serum | 25.65 (7, 113) | 46 (9, 140) | 22.5 (5, 116) | 0,043 | 25.65 (5, 140) | 22 (8, 66) | 0,708 | 22 (14.5, 35.5) | 32 (8.5, 41.5) | 0.751 |
| Pleura | 22 (4, 132) | 31.5 (0.4, 1.28) | 12 (2, 52) | 0,001 | 18 (4, 132) | 12 (2, 50) | 0,030 | 22 (12, 34) | 21.5 (7.2, 32.5) | 0.627 | |
| VDBP (mg/L) | Serum | 203 (29, 494) | 275.10 (13.13, 730) | 197 (27, 1122) | 0,1 | 236 (13, 730 | 190 (27, 1122) | 0,307 | 139 (29, 285) | 166 (42, 338) | 0.71 |
| Pleura | 134 (4, 834) | 191 (5, 464) | 95 (10, 446) | 0,001 | 155 (4, 834) | 95 (10, 446) | 0,48 | 85 (10, 183) | 217 (30, 258) | 0.112 | |
| LL-37 (ng/mL) | Serum | 0.84 (0.01, 153) | 0.47 (0.01, 12.62) | 0.25 (0.01, 10.34) | 0.017 | 0.67 (0.01, 153) | 0,.24 (0.01, 10.3) | 0.017 | 0,51 (0.28, 1.29) | 1.43 (0.95, 1.85) | 0.029 |
| Pleura | 1.42 (0.05, 153) | 0.52 (0.01, 13.51) | 0.3 (0.01, 3.3) | 0.001 | 0.91 (0.01, 153) | 0.3 (0.01, 3.3) | 0..001 | 1.05 (0.47, 4.28) | 3.11 (1,62, 5.62) | 0.014 | |
| β-defensin-2 (pg/mL) | Serum | 232 (14, 2100) | 224 (10, 3000) | 284 (9, 1834 | 0.966 | 213 (9, 3000) | 258 (9, 1834) | 0.651 | 431 (136, 1015) | 112 (71, 233) | 0.023 |
| Pleura | 265.2 (6, 1293) | 276 (25, 3000) | 241 (5, 2206) | 0.706 | 240 (6, 3000) | 214 (5, 2206) | 0.484 | 383 (72, 804) | 152 (16, 352) | 0.091 | |
IE Infectious effusions, CHFE Congestive heart failure effusions, ME Malignant effusions, CIE Complicated infectious effusions, NCIE Non complicated infectious effusions, WBC White blood cells, N Neutrophils, LDH Lactate Dehydrogenase, VDBP Vitamin D Binding Protein, LL-37 Leucin leucin 37 (Cathelicidin). Data presented as mean ± SD for parametric results and mean (interquartilic range)