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. 2016 Jul 8;16:431. doi: 10.1186/s12885-016-2468-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — MiRNA 29b mimic targeted DNMT 3B and reversed EMT. a Q-PCR examination of miRNA 29b expression in A253 cells. * indicated p < 0.05 and ** indicated p < 0.01 as compared with A253-0. # indicated that there were no statistically significant between A253-5 and A253-5si (Knockdown of DNMT 3B). b Transfection of miRNA 29b mimic could downregulate DNMT 3B and reverse EMT marker genes in A253-5. c, d Migration and invasion assay. Knockdown DNMT 3B by small interfering RNA or mir-29b mimic could inhibit cell mobility. * indicated p < 0.05, ** indicated p < 0.01 and *** indicated p < 0.001 as compared with A253-5