Table 2.
Prioritized AD candidate genes
| Intersected genes between healthy and AD PPI | MiRNAs | Differentially expressed neighbors | Number of literature articles for intersected genes | |
|---|---|---|---|---|
| Healthy PPI | AD PPI | |||
| APP | MIR101-1, | ADAM10, | TGFB1, | |
| MIR106A, | MAPT, | BACE1, | ||
| MIR106B, | MIF, | LRP1 | ||
| MIR124-1, | BACE1, | 24550 | ||
| MIR137, | LRP1 | |||
| MIR153-1, | ||||
| MIR181-C, | ||||
| MIR29A, | ||||
| MIR520C, | ||||
| MIR19-1 | ||||
| BACE1 | MIR107, | |||
| MIR124-1, | APP, | |||
| MIR145, | APP | LRP1 | 1883 | |
| MIR298, | ||||
| MIR29A, | ||||
| MIR29B1, | ||||
| MIR328, | ||||
| MIR9-1 | ||||
| ADAM10 | MIR451, | |||
| MIR144, | ||||
| MIR1306, | APP | - | 231 | |
| MIR107, | ||||
| MIR103 | ||||
| IL1B | MIR146A, | |||
| MIR155 | PTGS2 | - | 1099 | |
| MAPK3 | MIR15A, | - | STMN2, | 276 |
| MIR155 | JUN | |||
| MAPT | MIR16-1, | APP | TUBA4A | 3367 |
| MIR132 | ||||
| APLP2 | MIR153-1 | - | - | 134 |
| DLG4 | MIR485 | - | LRP1 | 151 |
| IL6 | MIR27B | - | - | 748 |
| JUN | MIR144 | - | STAT4, | 142 |
| MAPK3 | ||||
| LRP1 | MIR205 | APP | DLG4, | 305 |
| APP, | ||||
| BACE1 | ||||
| PTGS2 | MIR146A | IL1B | - | 474 |
| TGFB1 | MIR155 | - | APP | 276 |
This table summarizes the literature based evidences of intersected genes between healthy and AD PPI and their corresponding miRNAs and differentially expressed genes