Skip to main content
. Author manuscript; available in PMC: 2016 Jul 9.
Published in final edited form as: Neurosci Biobehav Rev. 2014 Apr 23;43:183–190. doi: 10.1016/j.neubiorev.2014.04.009

Fig. 5.

Fig. 5

Developmental modifications to AMPA receptors and NMDA receptors at excitatory synapses in the hippocampus. (A) During the third postnatal week, NMD A receptors with GluN2B subunits (blue) are replaced by NMDA receptors with GluN2A subunits (green). (B) From P17 to P24, expression of the AMPA receptor subunit, GluA1 (red), decreases while expression of GluA3 (yellow) and transmembrane AMPA receptor regulatory protein TARP (brown) increase. Synapse associated protein (SAP102) and postsynaptic density protein (PSD95) are anchoring proteins (orange) for AMPA and NMDA receptors at glutamatergic synapses (Elias et al., 2008). TARP regulates synaptic anchoring and AMPA receptor channel dynamics (Jackson and Nicoll, 2011). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of the article.)