Table 3.

Predictors of Adverse Drug Reactions Among Patients Receiving Ceftaroline (n=96)

Patient Characteristics	ADR (n=20)	No ADR (n=76)	P value*
Age, Med [IQR]	39 [32,65]	60 [42,71]	0.05
Female Sex, n (%)	12 (60)	40 (53)	0.62
White Race, n (%)	19 (95)	69 (91)	0.65
Comorbidities, n (%)
Atopy	2 (10)	10 (13)	1.00
Hypertension	7 (35)	43 (57)	0.13
Diabetes Mellitus	9 (45)	23 (30)	0.29
Coronary or peripheral vascular disease	3 (15)	24 (32)	0.17
Chronic Kidney Disease,	2 (10)	18 (24)	0.23
Hepatitis C Infection	0 (0)	11 (15)	0.11
HIV Infection	0 (0)	4 (5)	0.58
Intravenous Drug Use	5 (25)	12 (16)	0.34
Any drug allergy	12 (60)	51 (67)	0.60
Penicillin allergy	3 (15)	17 (23)	0.55
Cephalosporin allergy	2 (10)	11 (15)	1.00
Treatment Characteristics
Doses of ceftaroline, Med [IQR]	46 [21, 104]	21 [6, 59]	0.01
Off label indications, n (%)	15 (75)	42 (55)	0.13

^*Wilcoxan rank sum test for continuous variables and Fisher’s Exact for binary variables