Table 2.
Correlations between MMP-2, MMP-7, and MMP-9 expressions in tumor cells and clinicopathological parameters.
| Variables | Patients, N (%) | MMP-2 | MMP-7 | MMP-9 | |||
|---|---|---|---|---|---|---|---|
| R | p value | R | p value | R | p value | ||
| Gender | |||||||
| Male | 23 (79.3) | 0.460 | 0.013 | −0.047 | 0.814 | −0.042 | 0.804 |
| Female | 6 (20.7) | ||||||
| Age | |||||||
| ≤60 | 14 (48.3) | −0.012 | 0.949 | 0.339 | 0.071 | −0.383 | 0.046 |
| >60 | 15 (51.7) | ||||||
| Inflammation | |||||||
| Absent | 2 (6.9) | 0.690 | <0.001 | 0.053 | 0.782 | 0.081 | 0.666 |
| Weak | 9 (31.0) | ||||||
| Moderate | 10 (34.5) | ||||||
| Strong | 8 (27.6) | ||||||
| Desmoplasia | |||||||
| Poor | 12 (41.4) | 0.016 | 0.931 | 0.215 | 0.262 | 0.135 | 0.491 |
| Prominent | 17 (58.6) | ||||||
| Foci of hemorrhage | |||||||
| Absent | 14 (48.3) | 0.088 | 0.648 | 0.161 | 0.403 | −0.271 | 0.162 |
| Single | 10 (34.5) | ||||||
| Numerous | 5 (17.2) | ||||||
| Necrosis | |||||||
| Absent | 16 (55.2) | −0.007 | 0.968 | 0.402 | 0.031 | 0.084 | 0.668 |
| Weak | 7 (24.1) | ||||||
| Moderate | 6 (20.7) | ||||||
| Strong | 0 (0.0) | ||||||
| MVD | |||||||
| Low | 15 (51.7) | 0.072 | 0.738 | −0.682 | <0.001 | 0.368 | 0.084 |
| High | 14 (48.3) | ||||||
| Adenocarcinoma type | |||||||
| Nonmucinous | 26 (89.7) | −0.193 | 0.314 | −0.139 | 0.495 | −0.081 | 0.681 |
| Mucinous | 3 (10.3) | ||||||
| Grade of malignancy | |||||||
| G2 | 25 (86.2) | −0.156 | 0.417 | −0.036 | 0.850 | −0.129 | 0.512 |
| G3 | 4 (13.8) | ||||||
| Lymph node involvement | |||||||
| Absent | 17 (58.6) | 0.024 | 0.899 | −0.261 | 0.172 | 0.033 | 0.866 |
| Present | 12 (41.4) | ||||||
| Distant metastases | |||||||
| Absent | 20 (69.0) | 0.014 | 0.940 | −0.193 | 0.313 | −0.081 | 0.681 |
| Present | 9 (31.0) | ||||||