Table 3.
Correlations between MMP-2, MMP-7, and MMP-9 expressions in peritumoral stroma cells and clinicopathological parameters.
| Variables | Patients, N (%) | MMP-2 | MMP-7 | MMP-9 | |||
|---|---|---|---|---|---|---|---|
| R | p value | R | p value | R | p value | ||
| Gender | |||||||
| Male | 23 (79.3) | −0.051 | 0.793 | −0.603 | 0.060 | −0.237 | 0.215 |
| Female | 6 (20.7) | ||||||
| Age | |||||||
| ≤60 | 14 (48.3) | 0.199 | 0.299 | 0.029 | 0.879 | −0.261 | 0.170 |
| >60 | 15 (51.7) | ||||||
| Inflammation | |||||||
| Absent | 2 (6.9) | 0.263 | 0.167 | 0.132 | 0.494 | −0.042 | 0.826 |
| Weak | 9 (31.0) | ||||||
| Moderate | 10 (34.5) | ||||||
| Strong | 8 (27.6) | ||||||
| Desmoplasia | |||||||
| Poor | 12 (41.4) | 0.033 | 0.864 | −0.129 | 0.505 | 0.189 | 0.325 |
| Prominent | 17 (58.6) | ||||||
| Foci of hemorrhage | |||||||
| Absent | 14 (48.3) | −0.198 | 0.302 | −0.010 | 0.958 | −0.164 | 0.395 |
| Single | 10 (34.5) | ||||||
| Numerous | 5 (17.2) | ||||||
| Necrosis | |||||||
| Absent | 16 (55.2) | −0.196 | 0.306 | −0.050 | 0.796 | 0.121 | 0.529 |
| Weak | 7 (24.1) | ||||||
| Moderate | 6 (20.7) | ||||||
| Strong | 0 (0.0) | ||||||
| MVD | |||||||
| Low | 15 (51.7) | −0.220 | 0.300 | −0.022 | 0.916 | −0.046 | 0.829 |
| High | 14 (48.3) | ||||||
| Adenocarcinoma type | |||||||
| Nonmucinous | 26 (89.7) | −0.440 | 0.005 | 0.106 | 0.584 | −0.194 | 0.313 |
| Mucinous | 3 (10.3) | ||||||
| Grade of malignancy | |||||||
| G2 | 25 (86.2) | −0.130 | 0.500 | 0.125 | 0.518 | −0.021 | 0.912 |
| G3 | 4 (13.8) | ||||||
| Lymph node involvement | |||||||
| Absent | 17 (58.6) | −0.021 | 0.910 | −0.176 | 0.360 | −0.105 | 0.586 |
| Present | 12 (41.4) | ||||||
| Distant metastases | |||||||
| Absent | 20 (69.0) | 0.101 | 0.602 | −0.106 | 0.582 | −0.224 | 0.241 |
| Present | 9 (31.0) | ||||||