Skip to main content
. Author manuscript; available in PMC: 2016 Jul 10.
Published in final edited form as: J Cyst Fibros. 2011 Mar 26;10(4):243–252. doi: 10.1016/j.jcf.2011.03.001

Fig. 3.

Fig. 3

Additive effect of curcumin and genistein on G551D-CFTR whole-cell currents. (A) Representative whole-cell current trace from G551D-CFTR expressed in CHO cells, showing the additive effect of curcumin and genistein. Representative of eleven data. (B) The I–V relationships of the net G551D-CFTR whole-cell currents. The net whole-cell currents were obtained by subtracting the (leak) whole-cell currents at I from the whole-cell currents at II (control), III (genistein) and IV (genistein+curcumin) in Fig. 3A. (C) Comparison of fold-increases in the G551D-CFTR whole-cell currents (IWC) in control, induced by 10–80 μM genistein alone and additional applications of 5–30 μM curcumin to different genistein concentrations. Error bars represent SEM. ANOVA, *: P<0.05; **: P<0.01.