Table 2.

Multivariable covariate-adjusted hazard ratios for all cause and lung cancer specific mortality

Patient Characteristics	All Cause HR* (95% CI†)	All Cause P-value	Lung Cancer-specific HR* (95% CI†)	Lung Cancer-specific P-value
Prior cancer diagnosis (vs. None)
Yes (any)	0.95 (0.92–0.97)	<0.001	0.82 (0.80–0.85)	<0.001
Age (years; vs. 66–74)
75 – 85	1.16 (1.14–1.19)	<0.001	1.15 (1.13–1.18)	<0.001
> 85	1.33 (1.29–1.37)	<0.001	1.28 (1.23–1.32)	<0.001
Sex (vs. female)
Male	1.14 (1.12–1.17)	<0.001	1.14 (1.12–1.17)	<0.001
Race/ethnicity (vs. white)
Black	0.96 (0.93–0.99)	0.009	0.94 (0.91–0.98)	0.001
Hispanic	0.91 (0.83–1.00)	0.039	0.91 (0.83–1.01)	0.078
Other	0.85 (0.81–0.89)	<0.001	0.86 (0.81–0.90)	<0.001
Marital Status (vs. married)
Sep/Div/Wid‡	1.05 (1.03–1.07)	<0.001	1.03 (1.01–1.06)	0.005
Single	1.09 (1.05–1.13)	<0.001	1.08 (1.03–1.13)	<0.001
Unknown	1.07 (1.01–1.12)	0.016	1.05 (0.99–1.12)	0.091
Histology (vs. other non-small cell lung cancer [NSCLC])
Small Cell	1.20 (1.17–1.24)	<0.001	1.29 (1.25–1.33)	<0.001
Adenocarcinoma	0. 88 (0.86–0.90)	<0.001	0.92 (0.90–0.94)	<0.001
Squamous	0.94 (0.92–0.97)	<0.001	0.97 (0.95–1.00)	0.071
Comorbidity (vs. none)
One	1.11 (1.08–1.13)	<0.001	1.06 (1.04–1.09)	<0.001
Two or more	1.24 (1.21–1.27)	<0.001	1.12 (1.09–1.15)	<0.001
Rule out	0.93 (0.90–0.97)	0.001	0.93 (0.88–0.97)	<0.001
Payer Status (vs. no)
Medicaid	1.04 (1.01–1.06)	0.006	1.02 (0.99–1.05)	0.247
Treatment Status (vs. no Treatment)
Surgery only	0.3 (0.29–0.31)	<0.001	0.27 (0.26–0.29)	<0.001
Chemotherapy only	0.52 (0.50–0.53)	<0.001	0.55 (0.53–0.57)	<0.001
Radiation only	0.62 (0.60–0.64)	<0.001	0.66 (0.64–0.68)	<0.001
Two or more	0.36 (0.35–0.37)	<0.001	0.38 (0.37–0.39)	<0.001

^*HR denotes hazard ratio of all cause and lung cancer specific death for the above covariates

^†CI denotes confidence interval

^‡Separated/Divorced/Widowed