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. Author manuscript; available in PMC: 2016 Dec 30.
Published in final edited form as: Nature. 2016 Jun 30;534(7609):710–713. doi: 10.1038/nature18302

Fig. 2. Changes in the mitochondrial proteome upon UPRmt induction.

Fig. 2

a, Volcano plot showing fold changes versus p-values for total quantified and quantified mitochondrial proteins. b, Volcano plot showing fold changes versus p-values for quantified mitochondrial proteins. Proteins significantly changing are indicated by green dots, c, Heatmap organized by GO groups of mitochondrial protein level changes. Proteins which didn't change significantly, grey. d, Histogram of protein (panel b) and/or mRNA (Fig. 1) abundance for chaperonin and mitochondrial RNase P subunits. Two-tailed p-values *p≤0.05, **p≤0.01, ***p≤0.001, mean of n=3 (RNA) or n=2 (protein) biological replicates. n.s. not significant. # p-value of 0.06.