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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Brain Behav Immun. 2016 Apr 1;56:281–288. doi: 10.1016/j.bbi.2016.03.025

Table 3. Significant Predictors of Psychomotor Speed in Patients with MDD.

Adjusted
R2
beta Uncorrected
p
Corrected
p
SMT 0.16 IL-6 0.28 0.008 0.012
HamD 0.24 0.018 0.021
CMT 0.18 IL-6 0.26 0.021 0.032
Sex 0.27 0.012 0.015
Age 0.24 0.019 0.027
SRT 0.19 Sex 0.25 0.018 0.024
CRT 0.17 BMI 0.31 0.005 0.003**
Age 0.23 0.025 0.044
FTT 0.18 MCP-1 −0.26 0.015 0.018
sTNFR2 0.27 0.020 0.029
BMI −0.33 0.006 0.006**
Sex −0.21 0.045 0.050
DSST 0.15 IL-10 0.28 0.007 0.009
MCP-1 −0.23 0.027 0.047
Education 0.24 0.022 0.038
Trails A 0.11 BMI 0.24 0.021 0.035
Education −0.24 0.023 0.041
Factor Score* 0.26 IL-6 0.25 0.025
BMI 0.341 0.004
Age 0.21 0.029

SMT: Simple Choice Movement Time; CMT: Five Choice Movement Time; SRT: Simple Choice Reaction Time; CRT: Five Choice Reaction Time; FTT: DSST: Digit Symbol Substitution Task; Finger Tapping Task; HamD: Hamilton Depression Rating Scale; BMI: Body Mass Index; hsCRP: high sensitivity C-reactive protein; IL-6: interleukin 6; TNF alpha: tumor necrosis factor alpha; IL-1 beta: interleukin 1 beta; IL-10: interleukin 10; sTNFR2: soluble tumor necrosis factor receptor 2; sIL-6R: soluble interleukin 6 receptor; IL-1RA: interleukin 1 receptor antagonist; MCP-1: monocyte chemoattractant protein 1; All results are expressed as the natural log (Ln) of the indicated variables, except for the Factor Score, which was calculated from the Ln of the individual psychomotor tasks; Beta denotes the standardized estimate;

*

p values uncorrected; Corrected p values based on Benjamini Hochberg <0.05;

**

Corrected p value not significant based on Benjamini Hochberg procedure for determination of significance