Table 3. Significant Predictors of Psychomotor Speed in Patients with MDD.
Adjusted R2 |
beta |
Uncorrected
p |
Corrected
p |
||
---|---|---|---|---|---|
SMT | 0.16 | IL-6 | 0.28 | 0.008 | 0.012 |
HamD | 0.24 | 0.018 | 0.021 | ||
CMT | 0.18 | IL-6 | 0.26 | 0.021 | 0.032 |
Sex | 0.27 | 0.012 | 0.015 | ||
Age | 0.24 | 0.019 | 0.027 | ||
SRT | 0.19 | Sex | 0.25 | 0.018 | 0.024 |
CRT | 0.17 | BMI | 0.31 | 0.005 | 0.003** |
Age | 0.23 | 0.025 | 0.044 | ||
FTT | 0.18 | MCP-1 | −0.26 | 0.015 | 0.018 |
sTNFR2 | 0.27 | 0.020 | 0.029 | ||
BMI | −0.33 | 0.006 | 0.006** | ||
Sex | −0.21 | 0.045 | 0.050 | ||
DSST | 0.15 | IL-10 | 0.28 | 0.007 | 0.009 |
MCP-1 | −0.23 | 0.027 | 0.047 | ||
Education | 0.24 | 0.022 | 0.038 | ||
Trails A | 0.11 | BMI | 0.24 | 0.021 | 0.035 |
Education | −0.24 | 0.023 | 0.041 | ||
Factor Score* | 0.26 | IL-6 | 0.25 | 0.025 | |
BMI | 0.341 | 0.004 | |||
Age | 0.21 | 0.029 |
SMT: Simple Choice Movement Time; CMT: Five Choice Movement Time; SRT: Simple Choice Reaction Time; CRT: Five Choice Reaction Time; FTT: DSST: Digit Symbol Substitution Task; Finger Tapping Task; HamD: Hamilton Depression Rating Scale; BMI: Body Mass Index; hsCRP: high sensitivity C-reactive protein; IL-6: interleukin 6; TNF alpha: tumor necrosis factor alpha; IL-1 beta: interleukin 1 beta; IL-10: interleukin 10; sTNFR2: soluble tumor necrosis factor receptor 2; sIL-6R: soluble interleukin 6 receptor; IL-1RA: interleukin 1 receptor antagonist; MCP-1: monocyte chemoattractant protein 1; All results are expressed as the natural log (Ln) of the indicated variables, except for the Factor Score, which was calculated from the Ln of the individual psychomotor tasks; Beta denotes the standardized estimate;
p values uncorrected; Corrected p values based on Benjamini Hochberg <0.05;
Corrected p value not significant based on Benjamini Hochberg procedure for determination of significance