Table 2.
Volumetric comparisons in the selected regions of interest (ROIs) between the postural instability gait difficulty (PIGD) subtype, tremor dominant (TD) subtype and HCs.
| Region | Estimated mean controls (n = 28) | Estimated mean PIGD (n = 30) | Estimated mean TD (n = 30) | Group (healthy controls, PIGD and TD subtypes) F value (p-value) |
|---|---|---|---|---|
| Cerebellum | 50513 ± 1420 | 49304 ± 1317 | 49567 ± 1403 | 0.21 (0.81) |
| Thalamus | 6303 ± 126 | 6430 ± 118 | 6653 ± 89 | 1.78 (0.18) |
| Caudate | 3707 ± 99 | 3287 ± 91 | 3363 ± 97 | 5.34 (0.007) |
| Putamen | 4947 ± 109 | 4475 ± 101 | 4738 ± 108 | 5.29 (0.007) |
| Globus pallidus | 1397 ± 37 | 1387 ± 35 | 1509 ± 37 | 3.20 (0.046) |
| Hippocampus | 3824 ± 52 | 3724 ± 87 | 3817 ± 77 | 0.41 (0.66) |
| Amygdala | 1693 ± 50 | 1391 ± 46 | 1535 ± 50 | 9.95 (0.0001) |
| Nucleus accumbens | 586 ± 20 | 539 ± 18 | 561 ± 19 | 1.63 (0.20) |