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. 2016 May;5(1):57–64. doi: 10.15420/aer.2016.2.3

Table 1: Recommendations for Permanent Pacing in Adults with Complex CHD.

Class Clinical Indication Level of Evidence
Class I Symptomatic SND, including documented sinus bradycardia or chronotropic incompetence that is intrinsic or secondary to required drug therapy C
Symptomatic bradycardia in conjunction with any degree of AV block or with ventricular arrhythmias presumed to be because of AV block B
Postoperative high-grade second- or third-degree AV block that is not expected to resolve C
Class IIa Impaired haemodynamics, as assessed by non-invasive or invasive means, due to sinus bradycardia or loss of AV synchrony C
Sinus or junctional bradycardia for the prevention of recurrent IART C
Adults with complex CHD and an awake resting heart rate (sinus or junctional) <40 bpm or ventricular pauses >3 seconds C
Class IIb Adults with CHD of moderate complexity and an awake resting heart rate (sinus or junctional) <40 bpm or ventricular pauses >3 seconds C
History of transient postoperative complete AV block, and residual bifascicular block C
Class III Pacing is not indicated in asymptomatic adults with CHD and bifascicular block with or without first-degree AV block in the absence of a history of transient complete AV block C
Endocardial leads are generally avoided in adults with CHD and intracardiac shunts B

AV = atrioventricular; CHD = congenital heart disease; IART = intra-atrial re-entrant tachycardia; SND = sinus node dysfunction. Adapted from Khairy, et al., 2014.2