Table 3.
Clinicopathological features of the study population according to MSI status.
| Total | MSI-H | MSI-L | MSS | p value | ||
|---|---|---|---|---|---|---|
| N | N (%) | N (%) | N (%) | |||
| Patients | 158 | 35 (22.2) | 21 (13.3) | 102 (64.55) | ||
|
| ||||||
| Mean age | Years | 50.32 | 49.6 | 53.16 | 0.155 | |
|
| ||||||
| Gender | Female | 82 | 11 (31.4) | 11 (52.4) | 60 (58.8) | 0.019 |
| Male | 76 | 24 (68.6) | 10 (47.6) | 42 (41.2) | ||
|
| ||||||
| Location of tumor | Colon | 92 | 27 (77.1) | 11 (52.4) | 54 (52.9) | 0.030 |
| Rectum | 66 | 8 (22.9) | 10 (47.6) | 48 (47.1) | ||
|
| ||||||
| Differentiation | Well | 64 | 8 (22.9) | 9 (42.9) | 47 (46.1) | 0.003 |
| Moderately | 51 | 8 (22.9) | 7 (33.3) | 36 (35.3) | ||
| Poorly | 39 | 19 (54.3) | 5 (23.8) | 19 (18.6) | ||
|
| ||||||
| TNM stage | I | 21 | 3 (8.6) | 2 (9.5) | 16 (15.7) | 0.028 |
| II | 73 | 11 (31.4) | 10 (47.6) | 52 (51.0) | ||
| III | 57 | 21 (60.0) | 8 (38.1) | 28 (27.5) | ||
| IV | 7 | — | 1 (4.8) | 6 (5.9) | ||
|
| ||||||
| T stage | (T1 : T2 : T3 : T4) | 4 (11.4) : 2 (5.7) : 29 (82.9) : — | 1 (4.8) : 2 (9.5) : 15 (71.4) : 3 (14.3) | 16 (15.7) : 11 (10.8) : 66 (64.7) : 9 (8.8) | 0.104 | |
|
| ||||||
| N stage | (N0 : N1 : N2) | 14 (40.0) : 17 (48.6) : 4 (11.4) | 12 (57.1) : 7 (33.3) : 2 (9.5) | 71 (69.6) : 25 (24.5) : 6 (5.9) | 0.043 | |
|
| ||||||
| M stage | (M0 : M1) | 35 (100) : — | 20 (95.2) : 1 (4.8) | 96 (94.1) : 6 (5.6) | 0.162 | |
|
| ||||||
| Family history | Yes | 70 | 24 (68.5) | 9 (42.9) | 37 (36.3) | <0.0001 |
| No | 88 | 11 (31.4) | 12 (57.1) | 65 (63.7) | ||
|
| ||||||
| Adjuvant therapy | Yes | 39 | 2 (10.5) | 7 (33.3) | 30 (29.4) | 0.054 |
| No | 119 | 33 (94.3) | 14 (66.7) | 72 (70.6) | ||
|
| ||||||
| Vital status | Living | 141 | 32 (91.4) | 17 (81.0) | 92 (90.2) | 0.463 |
| Deceased | 17 | 3 (8.6) | 4 (19.0) | 10 (9.8) | ||
|
| ||||||
| Age of diagnosis | <50 | 89 | 14 (40.0) | 15 (71.4) | 60 (58.8) | 0.049 |
| >50 | 69 | 21 (60.0) | 6 (26.6) | 42 (41.2) | ||
|
| ||||||
| Metastases | Yes | 29 | 2 (5.7) | 4 (19.0) | 23 (22.5) | 0.050 |
| No | 129 | 33 (94.3) | 17 (81.0) | 79 (77.5) | ||