Table 1.
Full List of Analytes Assessed in Study 1
| Analyte | F | p | Analyte | F | p |
|---|---|---|---|---|---|
| Leptin | 12.804 | 0.0007 | IL-4 | 1.351 | 0.25 |
| IL-17F | 8.016 | 0.006 | IL-5 | 1.353 | 0.25 |
| Eotaxin | 7.587 | 0.008 | IL-6 | 1.089 | 0.301 |
| VEGF | 6.93 | 0.011 | IL-7 | 1.022 | 0.317 |
| V-CAM1 | 6.723 | 0.012 | IL-8 | 0.975 | 0.327 |
| IFN-β | 6.134 | 0.016 | IP10 | 0.787 | 0.379 |
| CD40Ligand | 5.617 | 0.021 | LIF | 0.73 | 0.397 |
| ENA78 | 4.917 | 0.031 | M-CSF | 0.664 | 0.418 |
| FGFb | 4.433 | 0.04 | MCP-1 | 0.646 | 0.425 |
| G-CSF | 3.997 | 0.05 | MCP-3 | 0.622 | 0.433 |
| GM-CSF | 3.953 | 0.051 | MIG | 0.545 | 0.463 |
| GRO-α | 3.929 | 0.052 | MIP-1β | 0.474 | 0.494 |
| HGF | 3.929 | 0.052 | MIP-1α | 0.427 | 0.516 |
| ICAM-1 | 3.724 | 0.058 | NGF | 0.266 | 0.608 |
| IFN-α | 3.019 | 0.087 | PAI-1 | 0.234 | 0.63 |
| IFN-γ | 2.742 | 0.103 | PDGFBB | 0.209 | 0.649 |
| IL-10 | 2.484 | 0.12 | RANTES | 0.052 | 0.821 |
| IL-12 p70 | 2.488 | 0.121 | Resistin | 0.05 | 0.823 |
| IL-12 p40 | 2.435 | 0.124 | SCF | 0.034 | 0.855 |
| IL-13 | 2.419 | 0.125 | sFAS_lig | 0.018 | 0.892 |
| IL-15 | 2.201 | 0.143 | TGF-α | 0.009 | 0.926 |
| IL-17 | 2.212 | 0.144 | TGF-β | 0.001 | 0.988 |
| IL-1α | 1.963 | 0.166 | TNF-α | 0.001 | 0.995 |
| IL-1β | 1.89 | 0.174 | TNF-β | (below detection) | |
| IL-1Ra | 1.673 | 0.203 | Trail | (below detection) | |
| IL-2 | 1.353 | 0.249 | VCAM-1 | (below detection) | |
The significance threshold was Bonferroni adjusted to 0.001 (significant results are marked in bold font). Analytes are listed in descending order of statistical significance as a predictor of self-reported pain.
IFN, interferon; IL, interleukin; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; TGF, transforming growth factor; TNF, tumor necrosis factor.