Table 1. Comparison Between Leishmania Lesion Sizes After Eight Weeks of Treatment^a,b.

Treatment, w	Group 1	Group 2	P Valuec	Group 3	Group 4	P Valuec
One	1.53 ± 0.75	1.59 ± 0.62	0.953	1.76 ± 1.12	1.74 ± 0.93	0.758
Two	2.63 ± 1.25	2.25 ± 1.61	0.356	3.61 ± 0.85	2.52 ± 0.76	0.276
Three	3.68 ± 0.56	2.61 ± 1.56	0.391	6.92 ± 2.55	4.39 ± 1.57	0.096
Four	5.96 ± 0.34	3.11 ± 0.98	0.088	7.43 ± 3.86	5.33 ± 1.66	0.072
Five	6.88 ± 2.28	3.83 ± 1.55	0.031	9.11 ± 2.11	6.21 ± 2.54	0.033
Six	7.91 ± 3.56	4.32 ± 1.27	0.046	9.93 ± 4.38	6.85 ± 3.14	0.024
Seven	8.62 ± 3.25	4.58 ± 1.86	0.002	10.2 ± 5.84	7.12 ± 3.57	0.013
Eight	8.95 ± 5.71	4.81 ± 3.22	0.0001	10.8 ± 6.32	7.81 ± 4.22	0.003

^aGroup 1, placebo after inoculation; group 2, morphine ointment after inoculation; group 3, placebo after lesions present; group 4, morphine after lesions present.

^bP value < 0.05 is considered significant.

^cUsing independent Student’s t-test.