TABLE 5. Odds ratiosa and 95% confidence intervals of colorectal cancer according to median DASH score stratified by body mass index and sex, NECSS, Canada, 1994–1997.
| Cancer site | DASH Score |
p value for trend | ||||||
|---|---|---|---|---|---|---|---|---|
| ≤2 | 3 | 4 | 5 | 6 | 7 | ≥8 | ||
| BMI < 25.0 kg/m2 | ||||||||
| Colon (n = 629) | ||||||||
| Men (n = 274) | Ref. | 1.30 (0.68–2.51) | 0.84 (0.45–1.60) | 0.86 (0.45–1.63) | 1.39 (0.74–2.62) | 0.94 (0.48–1.85) | 0.69 (0.34–1.40) | .40 |
| Women (n = 355) | Ref. | 1.53 (0.79–2.96) | 1.49 (0.81–2.73) | 1.53 (0.82–2.84) | 2.09 (1.13–3.89) | 1.60 (0.84–3.05) | 1.65 (0.86–3.17) | .16 |
| Rectum (n = 546) | ||||||||
| Men (n = 268) | Ref. | 1.55 (0.80–3.01) | 1.34 (0.72–2.51) | 0.89 (0.46–1.72) | 1.25 (0.64–2.43) | 0.91 (0.45–1.83) | 0.50 (0.24–1.07) | .01 |
| Women (n = 278) | Ref. | 0.97 (0.51–1.84) | 0.77 (1.43–1.39) | 0.88 (0.48–1.60) | 0.91 (0.49–1.69) | 0.74 (0.39–1.40) | 1.04 (0.56–1.95) | .96 |
| Colorectum (n = 1175) | ||||||||
| Men (n = 542) | Ref. | 1.48 (0.87–2.52) | 1.18 (0.71–1.95) | 0.92 (0.55–1.55) | 1.40 (0.83–2.36) | 0.98 (0.57–1.70) | 0.64 (0.36–1.14) | .05 |
| Women (n = 633) | Ref. | 1.32 (0.79–2.20) | 1.10 (0.69–1.76) | 1.17 (0.72–1.89) | 1.43 (0.88–2.32) | 1.13 (0.68–1.87) | 1.32 (0.80–2.19) | .41 |
| BMI ≥ 25.0 kg/m2 | ||||||||
| Colon (n = 1084) | ||||||||
| Men (n = 681) | Ref. | 0.85 (0.55–1.32) | 1.13 (0.75–1.72) | 1.14 (0.75–1.72) | 1.13 (0.74–1.72) | 0.88 (0.56–1.38) | 0.61 (0.38–0.99) | .15 |
| Women (n = 403) | Ref. | 0.74 (0.44–1.24) | 1.03 (0.63–1.69) | 0.74 (0.45–1.21) | 0.73 (0.42–1.25) | 0.75 (0.44–1.30) | 0.78 (0.42–1.45) | .30 |
| Rectum (n = 891) | ||||||||
| Men (n = 586) | Ref. | 1.21 (0.77–1.91) | 1.64 (1.05–2.56) | 1.45 (0.93–2.26) | 1.24 (0.79–1.96) | 1.06 (0.66–1.71) | 0.70 (0.41–1.17) | .07 |
| Women (n = 305) | Ref. | 1.02 (0.56–1.86) | 0.75 (0.41–1.38) | 1.10 (0.63–1.92) | 1.58 (0.90–2.80) | 1.06 (0.58–1.93) | 0.65 (0.50–1.82) | .47 |
| Colorectum (n = 1974) | ||||||||
| Men (n = 1267) | Ref. | 0.99 (0.68–1.43) | 1.35 (0.95–1.94) | 1.29 (0.91–1.84) | 1.18 (0.82–1.70) | 0.95 (0.65–1.39) | 0.65 (0.43–0.98) | .05 |
| Women (n = 707) | Ref. | 0.85 (0.53–1.36) | 0.88 (0.56–1.38) | 0.96 (0.62–1.48) | 0.85 (0.54–1.35) | 0.83 (0.52–1.33) | 0.93 (0.57–1.52) | .78 |
Abbreviations: BMI, body mass index; DASH, Dietary Approaches to Stop Hypertension; CI, confidence interval; OR, odds ratio; NECSS, National Enhanced Cancer Surveillance Study.
Note: Totals may vary due to missing values.
a
Adjusted for 10-year age group (20–49, 50–59, 60–69, 70–76 years), province, education, smoking, strenuous and moderate activity, calcium supplementation and age at first pregnancy for women.