Table 3.
Association between risk factors and colorectal adenomas according to subsite
| Variable | All subjects with adenoma (n = 618) | Subjects with right-sided adenoma only (n = 285) | Subjects with left-sided adenoma only (n = 157) |
|---|---|---|---|
| Age | 1.058 (1.044-1.072) | 1.053 (1.035-1.072) | 1.042 (1.020-1.064) |
| p trend | < 0.001 | < 0.001 | < 0.001 |
| Height quartile, group | |||
| 1 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 2 | 0.992 (0.725-1.356) | 1.147 (0.767-1.718) | 0.608 (0.369-0.999) |
| 3 | 0.989 (0.722-1.355) | 1.312 (0.880-1.957) | 0.635 (0.388-1.038) |
| 4 | 0.928 (0.679-1.270) | 1.093 (0.729-1.638) | 0.731 (0.458-1.167) |
| p trend | 0.965 | 0.597 | 0.162 |
| Body mass index, kg/m2 | 1.034 (0.989-1.080) | 1.059 (1.000-1.122) | 1.005 (0.937-1.077) |
| p trend | 0.141 | 0.052 | 0.888 |
| Metabolic syndrome | |||
| No | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| Yes | 1.005 (0.758-1.333) | 0.963 (0.674-1.377) | 0.665 (0.407-1.087) |
| p trend | 0.971 | 0.837 | 0.104 |
| Family history of CRC | |||
| No | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| Yes | 0.841 (0.486-1.455) | 0.834 (0.418-1.661) | 1.000 (0.447-2.237) |
| p trend | 0.536 | 0.605 | 0.999 |
| Smoking habit | |||
| Never | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| Past | 1.083 (0.805-1.458) | 1.002 (0.690-1.455) | 1.187 (0.725-1.942) |
| Current | 1.490 (1.075-2.065) | 1.092 (0.718-1.661) | 1.819 (1.081-3.059) |
| p trend | 0.023 | 0.872 | 0.040 |
| Alcohol intake | |||
| No | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| Yes | 1.015 (0.722-1.428) | 1.154 (0.740-1.801) | 0.805 (0.477-1.356) |
| p trend | 0.930 | 0.528 | 0.414 |
| Regular use of aspirin | |||
| No | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| Yes | 1.026 (0.767-1.374) | 1.028 (0.712-1.485) | 1.026 (0.643-1.638) |
| p trend | 0.862 | 0.883 | 0.913 |
Values are presented as odd ratio (95% confidence interval).
CRC, colorectal cancer.