Table 2.
Clinical characteristics of type 2 diabetes with and without subclinical hypothyroidism
| Characteristic | Euthyroidism (n = 628) |
Subclinical hypothyroidism (n = 50) |
||||
|---|---|---|---|---|---|---|
| Total | Men (n = 424) | Women (n = 204) | Total | Men (n = 23) | Women (n = 27) | |
| Age, yr | 55.3 ± 10.1 | 53.3 ± 9.6 | 59.4 ± 9.3 | 56.9 ± 8.1 | 56.6 ± 9.4 | 57.2 ± 6.9 |
| BMI, kg/m2 | 25.1 ± 2.9 | 25.2 ± 2.6 | 24.8 ± 3.5 | 25.7 ± 4.3 | 25.0 ± 2.7 | 26.3 ± 5.3 |
| Hypertension | 152 (24.2) | 99 (23.3) | 53 (26.0) | 18 (36.0) | 10 (43.5) | 8 (29.6) |
| Systolic BP, mmHg | 122.7 ± 12.7 | 122.7 ± 11.5 | 122.9 ± 14.9 | 125.0 ± 17.7 | 126.5 ± 14.6 | 123.7 ± 20.2 |
| Diastolic BP, mmHg | 79.0 ± 9.7 | 79.0 ± 8.9 | 78.9 ± 11.2 | 80.2 ± 12.0 | 82.1 ± 10.4 | 78.5 ± 13.2 |
| FPG, mg/dL | 135.9 ± 38.3 | 139.6 ± 38.3 | 128.3 ± 37.2 | 143.7 ± 51.6 | 139.1 ± 39.6 | 147.6 ± 60.5 |
| HbA1c, % | 7.5 ± 14 | 7.5 ± 1.3 | 7.4 ± 13 | 8.0 ± 2.0 | 7.6 ± 1.3 | 8.3 ± 2.3 |
| BUN, mg/dL | 14.8 ± 4.1 | 15.0 ± 3.9 | 14.4 ± 4.4 | 14.7 ± 3.6 | 15.0 ± 3.4 | 14.6 ± 3.8 |
| Creatinine, mg/dL | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.7 ± 0.1 | 0.9 ± 0.1 | 1.0 ± 0.1 | 0.7 ± 0.1 |
| Total cholesterol, mg/dL | 210.8 ± 43.1 | 206.6 ± 40.4 | 219.6 ± 47.2 | 207.1 ± 42.7 | 200.7 ± 42.3 | 212.5 ± 43.1 |
| Triglyceride, mg/dL | 189.2 ± 144.3 | 198.2 ± 152.6 | 170.5 ± 123.6 | 153.4 ± 70.4 | 147.9 ± 56.7 | 158.2 ± 81.1 |
| HDL-C, mg/dL | 53.5 ± 14.2 | 51.8 ± 12.85 | 57.08 ± 16.1 | 58.9 ± 18.5 | 57.0 ± 16.9 | 60.7 ± 19.9 |
| LDL-C, mg/dL | 119.4 ± 40.5 | 115.1 ± 39.3 | 128.4 ± 41.6 | 117.4 ± 40.4 | 114.0 ± 42.3 | 120.2 ± 39.4 |
| TSH, mIU/La | 1.6 ± 0.8 | 1.6 ± 0.8 | 1.8 ± 0.8 | 6.0 ± 2.4 | 6.1 ± 2.8 | 5.8 ± 2.1 |
| Free T4, ng/dL | 1.2 ± 0.4 | 1.3 ± 0.2 | 1.3 ± 0.2 | 1.2 ± 0.4 | 1.3 ± 0.2 | 1.2 ± 0.1 |
Values are presented as mean ± SD or number (%).
BMI, body mass index; BP, blood pressure; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; BUN, blood urea nitrogen; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; TSH, thyroid stimulating hormone; T4, thyroxine.
a
p values for comparison of the mean values between genders by a Student t test, p < 0.05.