Table 2.
Clinical and treatment features of 26 PPMSSs
| Case NO. | Age/Gender | Symptoms/preop course at initial Op | Smoking | Size (CM) | Location | Microscopically invasion | Microscopically margin | Lymph node metastasis | Treatment | Progression/interval | Outcome/Follow-up duration |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M/48 y | Cough, Dyspnea/24 m; Chest pain/1 m | NA | 15 | RLL | NA | NA | ND | Lobectomy | NA | NA |
| 2 | M/52 y | Cough, Expectoration, Blood in phlegm/4 d | NA | 3.5 | RLL | - | - | ND | Lobectomy | NA | NA |
| 3 | F/27 y | Cough, Expectoration/1 m | Never | 5 | RLL | pleura | - | - | Lobectomy, Lymph node dissection, Chemotherapy (EADM + IFO + DTIC) | NA | NA |
| 4 | F/42 y | Chest pain, Hemoptysis/6 m | Never | 13 | RMLL | pleura | - | - | Lobectomy, Lymph node dissection | NA | NA |
| 5 | M/30 y | Cough, Chest pain/15 d | 10 y | 24 | LP | ND | ND | ND | Chemotherapy (IFO + EADM + DDP) | NA | NA |
| 6 | M/27 y | Cough, Chest pain, Dyspnea/6 m; Blood in phlegm/1 w | Never | 15 | LLUL | ND | ND | ND | Biopsy only | Local lymph node metastasis/at presentation | DOD/11 m |
| 7 | F/53 y | Cough, Hemoptysis/6 m | Never | 6 | LUL | - | - | - | Lobectomy, Lymph node dissection, Chemotherapy (CTX + VCR + EADM) | Localized/45 m | DOD/51 m |
| 8 | M/20 y | Cough, Chest pain/NA | NA | 3 | RML | ND | ND | ND | Biopsy only | Intrapulmonary metastasis/at presentation | DOD/8 m |
| 9 | F/31 y | Cough, Dyspnea/2 m | NA | 15 | Anterior mediastinum | NA | NA | ND | Tumorectomy | Localized/6 m | DOD/12 m |
| 10 | F/72 y | Cough, Expectoration/3 d | NA | 5 | RLL | pleura | - | NA | Lobectomy, Lymph node dissection | Intrapulmonary metastasis/29 m | DOD/32 m |
| 11 | M/28 y | Cough/24 m; Hemoptysis/2 d | NA | 6 | LUL | - | - | NA | Lobectomy, Lymph node dissection | NA | NA |
| 12 | M/62 y | Cough, Blood in phlegm/3 m | 30 y | 11.6 | LL | ND | ND | ND | Bronchial artery infusion chemotherapy (FudR + DDP + NVB) | Intrapulmonary and thyriod metastasis/at presentation | DOD/15 m |
| 13 | F/34 y | Cough, Expectoration, Hemoptysis/1 m | Never | 3.5 | LLL | - | - | - | Lobectomy, Lymph node dissection, Chemotherapy (IFO + EADM) | Localized/26 m; Left chest wall/36 m;Left rib/39 m; Right lung and spine metastasis/51 m | AWD/52 m |
| 14 | M/26 y | Cough, Chest pain, Dyspnea/20 d | 7 y | 14 | LUL | pleura | + | ND | Lobectomy | Localized/8 m | DOD/11 m |
| 15 | F/38 y | Cough, Chest pain/NA | NA | 8 | LUL | NA | NA | ND | Lobectomy | NA | NA |
| 16 | F/46 y | Cough, Chest pain/24 m | Never | 2.3 | RUL | ND | ND | ND | Biopsy only | Brain metastasis/at presentation | DOD/10 m |
| 17 | F/39 y | Cough, Chest pain/1 m | Never | 10 | LUP | Lung; chest wall | - | - | Lobectomy, Lymph node dissection, Chemotherapy (DTIC + EADN) | Adrenal gland metastasis/2 m | DOD/15 m |
| 18 | M/46 y | Cough/NA | NA | 4.2 | LUL | - | - | ND | Lobectomy | Multiple organs metastasis/2 m | DOD/18 m |
| 19 | M/20 y | Asymptomatic | Never | 3.5 | RUP | - | - | ND | Tumorectomy, Chemotherapy (IFO + DDP + EADM), Radiotherapy | Left lung metastasis/24 m | AWD/24 m |
| 20 | M/36 y | Asymptomatic | Never | 4.5 | LLL | - | - | - | Lobectomy, Lymph node dissection | NO | NED/4 m |
| 21 | M/16 y | Cough, Hemoptysis/NA | Never | 6 | RL | pleura | + | ND | Partial tumorectomy | NO | DOD/18 m |
| 22 | M/22 y | Chest pain/2 w; Spontaneous hemopneumothorax/1+ w | 6 y | 5 | LP | lung | + | ND | Tumorectomy | NO | DOD/9 m |
| 23 | M/47 y | Chest pain, Dyspnea/5 m | 30 y | 18 | RL | ND | ND | ND | Chemotherapy (GT regimen) | NO | AWD/10 m |
| 24 | M/60 y | NA | 30 y | 7 | LUL | - | - | - | Lobectomy, Lymph node dissection, Postoperative | Localized/9 m | AWD/9 m |
| 25 | M/37 y | Cough, Expectoration,Chest pain, Dyspnea/1 m | 10 y | 4 | LUL | - | - | - | Lobectomy, Lymph node dissection | NO | NED/1 m |
| 26 | M/24 y | Dyspnea/3 m;Syncope/2 m | Never | 5.3 | Valvula bicuspidalis | myocardium | - | ND | Tumorectomy, Chemotherapy | Localized/2 m | DOD/26 m |
Abbreviation: NA not available, ND not done, “+” positive, “-” negative. W well-defined, I ill-defined, LLL left lower lobe, LUL left uper lobe, RLL right lower lobe, RUL right uper lobe, RML right middle lobe, RMLL right middle and lower lobe, LLUL left lower and uper lobe, LP left pleura, LUP left uper pleura, RUP right uper pleura, y year, m month, w week, d day, EADM Epirubicin, IFO Ifosfamide, DTIC Dacarbazine, DDP cis-Dichlorodiamineplatinum, CTX cyclophosphamide, VCR Vincristine, NVB vinorelbine, FudR 2'-deoxy-5-fluoro-uridin, MFSS monophasic fibrous synovial sarcoma, BSS biphasic synovial sarcoma, PDSS poorly differentiated synovial sarcoma