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. 2016 May 10;110(9):2016–2025. doi: 10.1016/j.bpj.2016.04.005

Figure 2.

Figure 2

Bilayer dynamics in C-dot-DMPC/DOPC SUVs. (A) Fluorescence anisotropy (excitation 375 nm, emission 463 nm) of C-dot-DMPC embedded in DOPC SUVs. 1) Control C-dot-DMPC/DOPC SUVs before addition of membrane-active compounds. Anisotropy was recorded after addition of 2) PMB (0.1 mM), 3) valproic acid (0.1 mM), or 4) Aβ1-40 (30 μM). 5) C-dot-DMPC embedded in SUVs composed of DOPC and cholesterol (7:3 mol ratio of DOPC/cholesterol). (B) Fluorescence lifetime decays of C-dot-DMPC embedded in the SUVs. (i) Control vesicles before addition of membrane-active compounds. (ii) C-dot-DMPC embedded in SUVs composed of DOPC and cholesterol (7:3 mol ratio of DOPC/cholesterol). (iii) After addition of PMB (0.1 mM) to the C-dot-DMPC/DOPC SUVs.