Figure 4.

FRAP experiments in C-dot-DMPC/DOPC SSBs. (A) AFM image of an SSB (left) and the corresponding height profile (right). The size of the AFM image is 1 μm × 1 μm. (B) Confocal fluorescence microscopy images (excitation at 405 nm, emission filter EM 445/60) recorded at different times after photobleaching by a 405 nm laser (time immediately after laser irradiation is defined as T = 0 s). The bleached region is indicated by the circle. Scale bar, 5 μm. (C) Recovery curves recorded upon incubation of the SSBs with different molecules: control SSB (i), PMB (ii), valproic acid (iii), and Aβ_1-40 (iv). Each experiment was repeated five times. To see this figure in color, go online.