Table 2.
Comparison of PFS by original Colorado scoring versus ReadMax scoring in the SATURN study (ReadMax population)
HR (p value) | |||
---|---|---|---|
Comparison | Colorado scoring | ReadMax scoring | |
All patients with data (n = 201) | Erlotinib FISH+ vs erlotinib not FISH+ | 0.73 (p = 0.136) | 0.53 (p = 0.003) |
Erlotinib FISH+ vs placebo FISH+ | 0.67 (p = 0.04) | 0.52 (p = 0.004) | |
FISH‐positive (%) | 55 | 38 | |
EGFR WT subgroup (n = 131) | Erlotinib FISH+ vs erlotinib not FISH+ | 1.20 (p = 0.48) | 0.65 (p = 0.143) |
Erlotinib FISH+ vs placebo FISH+ | 1.02 (p = 0.94) | 0.63 (p = 0.185) | |
FISH‐positive (%) | 51 | 27 |
WT, wild‐type