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. 2015 Jun 3;1(4):252–263. doi: 10.1002/cjp2.20

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© 2015 John Wiley and Sons Ltd and The Pathological Society of Great Britain and Ireland

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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AD‐induced AECII apoptosis is mediated by LC3B. (A) Representative Western blot images for LC3B, cleaved caspase 3, proSP‐C, cathepsin D and β‐actin from MLE12 cells transfected with scrambled siRNA (scr) or siRNA for LC3B (LC3B si) and treated with AD or vehicle for 8 h. Cells treated only with AD, vehicle or untreated cells were included as controls. Different parts from the same Western blots are separated by vertical lines. (B and C) Densitometry analysis of cleaved caspase 3 (B) and proSP‐C (C) to β‐actin ratio was calculated and is given as a percentage of untreated cells. *p < 0.05.