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. Author manuscript; available in PMC: 2017 May 4.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Apr 8;55(19):5770–5775. doi: 10.1002/anie.201600753

Scheme 1.

Scheme 1

Schematic illustration of the use of the rate of molecular self-assembly (controlled by numbers of enzymatic site) to amplify the difference of the expression level of ALPs in different cell lines.