Table 2.
DNA methylation levels, AUDIT and GSI scores for control individuals vs. patients at T1. DNA Methylation level errors are given as standard error of the mean (SE), questionnaire score errors are given as standard deviation (SD).
| Control individuals | Patients at T1 | P-value | |
|---|---|---|---|
| Site 1 (cg23779890) | 7.8 ± 0.2 | 6.6 ± 0.3 | 0.001 |
| Site 2 | 4.0 ± 0.1 | 3.6 ± 0.1 | 0.015 |
| Site 3 | 2.1 ± 0.1 | 1.9 ± 0.1 | 0.012 |
| Mean DNA methylation (sites 1 – 3) | 4.6 ± 0.1 | 4.0 ± 0.2 | 0.001 |
| AUDIT score | 4.9 ± 3.7 | 25.1 ± 6.1 | 5.1E-15 |
| GSI score | 0.16 ± 0.13 | 0.78 ± 0.54 | 1.7E-10 |