Skip to main content
. 2016 Jul 11;11(7):e0159091. doi: 10.1371/journal.pone.0159091

Table 1. Chromosomal aberrations in control BJ cells and BJ cells expressing Bcl-xL (wt) and Bcl-xL phosphorylation mutants at various cell population doublings.

Cell Population Doubling Karyotypes
BJ control (PD 43.3) 46,XY[22]
BJ control (PD 70.1) 46,XY[10]
pLenti (PD 53.7) 46,XY[22]
Bcl-xL wt (PD 52.0) 46,XY[22]
Bcl-xL S49A (PD 42.4) 46,XY[18]
Bcl-xL S49A (PD 53.6) 46,XY[20]
Bcl-xL S62A (PD 39.2) 46,XY,t(6;7)(q21;q32)[3]/46, XY[17]
Bcl-xL S62A (PD 55.3) 46,XY,add(16)p13.1[9]/48,XY,+2mar[2]/46,XY[10]
Bcl-xL S49/62A (PD 39.0) 46,XY[22]
Bcl-xL S49/62A (PD 52.1) 46,XY[7]
Bcl-xL S49D (PD 37.1) 46,XY,add(16)q2?2)[4]/46,XY[12]
Bcl-xL S49D (PD 54.1) 46,XY,i(18)(q10)[3]/46,XY[18]
Bcl-xL S62D (PD 40.1) 46,XY[22]
Bcl-xL S62D (PD 52.5) 46,XY,t(4:5)(p16:q15)[9]/47,XY,+7[3]/46,XY[5]
Bcl-xL S49/62D (PD 50.1) 46,XY[12]