Table 1.

Association between the expression of GEF-H1 and the clinicopathological features in patients with melanoma

Variables	Description	Number of patients	GEF-H1 expression		χ2	P-value
			Low	High
Primary tumor ulceration	With	38	14	24	3.695	0.055
	Without	22	3	19
Lymph node metastases	0	57	16	41	3.322	0.190
	1	1	1	0
	2–3	2	0	2
Distant metastases	No distant metastases	57	17	40	1.248	0.264
	Distant skin, subcutaneous or nodal metastases	3	0	3
Tumor thickness	≤4 mm	27	11	16	3.722	0.054
	>4 mm	33	6	27
TNM stage	I	5	2	3	13.931	0.003**
	II	22	12	10
	III	30	3	27
	IV	3	0	3

Notes:

^**GEF-H1 has correlation with TNM stage.

Abbreviation: GEF-H1, guanine nucleotide exchange factor H1.