Table 1.
Correlations between GPR56 expression and clinicopathological features in NSCLC patients
| Variables | Cases
|
GPR56 expression
|
P-value | |
|---|---|---|---|---|
| (n=157) | Negative (n=46) (%) | Positive (n=111) (%) | ||
| Sex | 0.588 | |||
| Female | 53 | 17 (32.1) | 36 (67.9) | |
| Male | 104 | 29 (27.9) | 75 (72.1) | |
| Age (years) | 0.858 | |||
| ≤60 | 87 | 26 (29.9) | 61 (70.1) | |
| >60 | 70 | 20 (28.6) | 50 (71.4) | |
| Smoking | 0.897 | |||
| Yes | 90 | 26 (28.9) | 64 (71.1) | |
| No | 67 | 20 (29.9) | 47 (70.1) | |
| Tumor size (cm) | 0.930 | |||
| ≤3 | 64 | 19 (29.7) | 45 (70.3) | |
| >3 | 93 | 27 (29.0) | 66 (71.0) | |
| Histological type | 0.532 | |||
| Adenocarcinoma | 88 | 24 (27.3) | 64 (72.7) | |
| Squamous cell carcinoma | 69 | 22 (31.9) | 47 (68.1) | |
| Differentiation | 0.411 | |||
| Well/moderate | 98 | 31 (31.6) | 67 (68.4) | |
| Poor | 59 | 15 (25.4) | 44 (74.6) | |
| TNM stage | 0.005* | |||
| I/II | 72 | 29 (40.3) | 43 (59.7) | |
| III/IV | 85 | 17 (20.0) | 68 (80.0) | |
| LN metastasis | 0.499 | |||
| Negative | 89 | 28 (31.5) | 61 (68.5) | |
| Positive | 68 | 18 (26.5) | 50 (73.5) | |
Note:
*
Statistically significant.
Abbreviations: GPR56, G protein-coupled receptor 56; LN, lymph node; NSCLC, non-small-cell lung carcinoma.