Table II.
Development of pregnant mice and fetal mice and the incidence of cleft palate in each group.
| Group (n=5) | Pregnant mouse weight gain (g) | Live fetus body weight (g) | Number of fetal mice
|
|||
|---|---|---|---|---|---|---|
| Total | Cleft palate | Stillbirth or absorbed fetus | Incidence of cleft palate (%) | |||
| Control | 2.05±0.43 | 1.08±0.10 | 33 | 0 | 0 | 0.00 |
| TCDD (28 µg/kg) | 1.79±0.57 | 1.06±0.11 | 31 | 29 | 1 | 93.55a |
Data are presented as the mean ± standard deviation. Pregnant mouse weight gain represents the weight increase from GD 0 to GD 16.5.
a
P<0.01 compared with the control group. TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; GD, gestation day.