Table 3.
Mean mRNA Expression Levels of Proinflammatory Cytokines and their Membrane-bound Receptors in the Lymphocytes of Schizophrenia Patients and Normal Control Subjects
| Variable | Normal Controls (n = 30) Mean ΔCT ± SD |
Schizophrenia Patients (n = 30) Mean ΔCT ± SD |
t | p |
|---|---|---|---|---|
| TNF-α | 9.06 ± .51 | 8.21 ± .47 | −6.71 | <.0001 |
| IL-1β | 7.79 ± .48 | 7.64 ± .54 | −1.14 | .26 |
| IL-6 | 13.61 ± .55 | 12.59 ± .65 | −6.56 | <.0001 |
| TNFR1 | 4.89 ± .48 | 4.53 ± .50 | −2.77 | .01 |
| TNFR2 | 4.77 ± .32 | 4.51 ± .39 | −2.79 | .01 |
| IL-1R1 | 7.48 ± .54 | 7.13 ± .44 | −3.00 | .004 |
| IL-1R2 | 5.76 ± .47 | 5.71 ± .47 | −.49 | .62 |
| IL-1RA | 3.05 ± .37 | 2.90 ± .38 | −1.55 | .13 |
| IL-6ST (Gp130) | 7.32 ± .53 | 7.14 ± .60 | −1.44 | .15 |
| IL-6R | 6.40 ± .53 | 6.22 ± .45 | −1.42 | .16 |