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. Author manuscript; available in PMC: 2016 Jul 11.
Published in final edited form as: Nat Neurosci. 2014 Oct 26;17(12):1798–1803. doi: 10.1038/nn.3850

Figure 4.

Figure 4

Performance on the ModBent overlaps with the anatomical site of hippocampal aging. (a) A voxel-based analysis of 35 individuals revealed that better performance on the ModBent task correlated with greater CBV in the body of the hippocampal circuit (top left). A transverse slice, onto which the hippocampal circuit mask was applied, shows that the correlation localized primarily to the dentate gyrus (bottom left; coronal section, color coded by degree of significance). A scatter plot (right) shows the association between ModBent performance and single-subject mean CBV from all significantly correlated voxels (β = −0.633, r2 = 0.465, P < 0.001). (b) A voxel-based analysis in the same group showed that better performance on a delayed retention task correlated with greater CBV in the EC (left). A scatter plot (right) shows the association between performance on this delayed retention task and single-subject mean CBV from all significantly correlated voxels (β = 0.693, r2 = 0.562, P < 0.001).