Table 4.
IH Death (n = 11) |
Alive IH (n = 125) |
p value | 1-year death (n = 20) |
Alive 1-year (n = 89) |
p value | ||
---|---|---|---|---|---|---|---|
Age, years | 84 (84-86) | 83 (80-87) | 0.28 | 84 (80-88) | 83 (80-87) | 0.43 | |
Female gender | 45.5% | 49.6% | 0.52 | 60.0% | 48.3% | 0.24 | |
BMI (kg/m2) | 24.7 (23-5-28.3) | 25.3 (22.4-29.6) | 0.65 | 24.9 (23.5-27.3) | 25.3 (22.9-30.2) | 0.81 | |
NYHA class | |||||||
II | 36.4% | 53.6% | 0.28 | 50.0% | 57.3% | 0.52 | |
IV | 54.6% | 41.6% | 50.0% | 37.1% | |||
SH | 72.7% | 70.4% | 0.59 | 55.0% | 68.5% | 0.19 | |
DM | 54.6% | 36.0% | 0.19 | 54.6% | 36.0% | 0.19 | |
CAD | 63.6% | 56.0% | 0.44 | 55.0% | 53.9% | 0.57 | |
Previous CABG | 27.3% | 25.6% | 0.57 | 30.0% | 23.6% | 0.37 | |
Previous PCI | 27.3% | 34.4% | 0.45 | 30.0% | 33.7% | 0.49 | |
PVD | 9.1% | 24.8% | 0.22 | 20.0% | 20.2% | 0.62 | |
COPD | 18.2% | 8.8% | 0.28 | 30.0% | 6.7% | 0.008 | |
CRF | 81.8% | 51.2% | 0.048 | 60.0% | 47.2 | 0.22 | |
PAH | 54.6% | 21.6% | 0.024 | 40.0% | 22.5% | 0.09 | |
euroSCORE | 31.2 (12.6-52.2) | 18.7 (11.2-30.7) | 0.09 | 31.2 (16.3-42.0) | 19.9 (10.4-28.2) | 0.006 | |
STS score | 14.2 (6.5-30.5) | 9.3 (4.8-20.8) | 0.25 | 22.6 (11.9-36.2) | 7.9 (4.4-19.6) | 0.0005 | |
EF < 50% (TEE) | 36.4% | 25.8% | 0.33 | 40.0% | 24.7% | 0.14 | |
Baseline Cr (mg/dL) | 1.3 (0.7-1.7) | 1.1 (0.9-1.50) | 0.59 | 1.3 (0.9-1.4) | 1.1 (0.9-1.3) | 0.46 | |
Baseline Hb (mg/dL) | 11.4 (10.2-12.9) | 11.8 (10.4-13.10 | 0.48 | 11.8 (9.0-12.9) | 11.8 (10.7-13.3) | 0.46 | |
Pre platelets (x 103/mm3) | 189 (127-250) | 195 (158-236) | 0.53 | 218 (148-247) | 193 (163-237) | 0.49 | |
Baseline BNP (pg/mL) | 770 (320-1260) | 227 (123-553) | 0.017 | 536 (149-836) | 230 (121-519) | 0.065 | |
Baseline CRP (mg/dL) | 1.8 (0.2-5.5) | 0.3 (0.2-1.0) | 0.96 | 1.7 (0.2-2.3) | 0.3 (0.2-1) | 0.01 | |
General anesthesia | 90.9% | 77.6% | 0.27 | 55.0% | 78.7% | 0.032 | |
TEE | 81.8% | 77.6% | 0.54 | 50.0% | 77.5% | 0.016 | |
Direct TAVI | 36.4% | 17.6% | 0.13 | 40.0% | 15.7% | 0.02 | |
Post-dilatation | 70.0% | 35.2% | 0.034 | 47.4% | 15.7% | 0.15 | |
AoR ≥ 2/4 | 12.5% | 5.5% | 0.40 | 15.0% | 4.6% | 0.12 | |
Blood transfusion post | 90.9% | 17.1% | < 0.0001 | 60.0% | 16.9% | 0.0002 | |
Cr in 72 hours (mg/dL) | 1.9 (1.1-3.4) | 1.2 (0.9-1.5) | 0.06 | 1.3 (1.0-2.3) | 1.2 (0.9-1.5) | 0.16 | |
ARF | 45.5% | 11.2% | 0.008 | 30.0% | 12.4% | 0.058 | |
Nadir Hb (mg/dL) | 8.1 (7.5-11.4) | 9.6 (8.2-10.9) | 0.32 | 8.1 (7.4-11.2) | 9.6 (8.3-10.9) | 0.13 | |
Platelets post (x 103/mm3) | 99 (71-128) | 143 (105-167) | 0.03 | 125 (73-175) | 143 (106-167) | 0.29 | |
Peak CRP (mg/dL) | 13.1 96.6-17.5) | 7.8 (4.7-11.0) | 0.04 | 13.1 (8.2-16-2) | 7.5 (4.4-10.6) | 0.001 |
IH: in-hospital; BMI: body mass index; NYHA, New York Heart Association; SH: systemic hypertension; DM: diabetes mellitus; CAD: coronary artery disease; CABG: coronary artery bypass grafting; PCI: percutaneous coronary intervention; PVD: peripheral vascular disease; COPD: chronic obstructive pulmonary disease; CRF: chronic renal failure; PAH: pulmonary arterial hypertension; STS: Surgeons Thoracic Society; EF: ejection fraction; Cr: serum creatinine; Hb: hemoglobin; BNP: type-B brain natriuretic peptide; CRP: C-reactive protein; TEE: transesophageal echocardiogram; TAVI: transcatheter aortic valve implantation; AoR: aortic regurgitation; ARF: acute renal failure.