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. Author manuscript; available in PMC: 2016 Aug 12.
Published in final edited form as: Oncogene. 2016 Jan 11;35(32):4179–4187. doi: 10.1038/onc.2015.483

Table 5.

Cox regression analysis. Univariate (top) and multivariate (bottom) regression analysis of prognostic features in the AMC-AJCCII-90 set

P-value Hazard ratio 95% CI
Univariate analysis
 Location 0.884 1.07 0.430–2.662
 Differentiation 0.580
 Differentiation (1) 0.297 1.643 0.646–4.179
 T-stage 0.320 0.534 0.155–1.840
 MSI 0.968 1.021 0.368–2.836
 CFTR expression 0.028 2.775 1.114–6.910
Multivariate analysis
 Location 0.909 1.063 0.374–3.021
 Differentiation 0.808
 Differentiation (1) 0.514 1.398 0.512–3.820
 T-stage 0.379 0.57 0.163–1.996
 MSI 0.209 2.289 0.628–8.340
 CFTR expression 0.022 3.584 1.205–10.664

The univariate and multivariate analysis both show that CFTR expression is an important prognostic determinant in the AMC-AJCCII-set.