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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Br J Haematol. 2016 Mar 15;174(2):235–248. doi: 10.1111/bjh.14046

Table IV.

Prognostic model for progression free survival and overall survival

Prognostic Score1 N HR 95% CI
Lower Limit
95% CI
Upper Limit
p-value
0 194 1
2 103 1.30 0.97 1.76 0.08
4 14 1.41 0.76 2.62 0.28
5 38 1.66 1.13 2.46 0.01
6 12 2.21 1.19 4.11 0.01
7 35 2.34 1.58 3.47 <0.0001
9 3 1.79 0.44 7.24 0.41
11 18 5.47 3.26 9.19 <0.0001
    Progression-free Survival Risk Groups
Low (Score 0) 194 1
Intermediate (Score 2,4,5) 155 1.40 1.08 1.82 0.01
High (Score 6,7,9) 50 2.28 1.61 3.22 <0.0001
Very high (Score 11) 18 5.47 3.26 9.19 <0.0001
Contrast
Intermediate vs. High 0.61 0.43 0.87 0.006
Intermediate vs. Very high 0.26 0.15 0.43 <0.0001
High vs. Very high 0.42 0.24 0.73 0.002
Overall Survival Risk Groups
Low (Score 0) 199 1
Intermediate (Score 2,4,5) 156 1.34 1.02 1.76 0.03
High (Score 6,7,9) 50 2.11 1.47 3.03 <0.0001
Very high (Score 11) 18 3.94 2.32 6.68 <0.0001
Contrast
Intermediate vs. High 0.63 0.44 0.91 0.02
Intermediate vs. Very high 0.34 0.20 0.58 <0.0001
High vs. Very high 0.54 0.30 0.96 0.03

N = number; HR = hazard ratio; CI = confidence interval; CR = complete response; PR = partial response; KPS = Karnofsky performance status; alloHCT=allogeneic haematopoietic cell transplantation; autoHCT= autologous haematopoietic cell transplantation;

1

Prognostic score determined by following:

KPS≥80 = 0 point, KPS <80 = 4 points.

Disease status CR or PR = 0 point, Chemoresistant = 5 points

Time from autoHCT to alloHCT ≥12 months = 0 point, <12 months = 2 points.