Table 5.
Serum components, anthropometrics, and blood pressures in 11 individuals with ADPKD by study visit.a
| Baseline | 2 weeks | 4 weeks | |
|---|---|---|---|
| Serum | |||
| Sodium (mEq/L) | 137 ± 2 | 138 ± 2 | 136 ± 1 |
| Potassium (mEq/L) | 3.8 ± 0.3 | 4.0 ± 0.3 | 4.1 ± 0.3** |
| Chloride (mEq/L) | 104 ± 2 | 103 ± 2 | 103 ± 2 |
| CO2 (mmol/L) | 27 ± 2 | 27 ± 2 | 28 ± 2 |
| Anion Gap (mEq/L) | 7 ± 2 | 7 ± 3 | 6 ± 2 |
| Glucose (mg/dL) | 83 ± 9 | 86 ± 10 | 87 ± 13 |
| BUN (mg/dL) | 20 ± 8 | 15 ± 8*** | 15 ± 9** |
| Creatinine (mg/dL) | 0.97 ± 0.24 | 0.98 ± 0.32 | 0.98 ± 0.28 |
| eGFR (ml/min/1.73 m2) | 84 ± 25 | 85 ± 27 | 83 ± 26 |
| Uric Acid (mg/dL) | 4.8 ± 1.6 | 4.7 ± 1.5 | 4.8 ± 1.5 |
| Calcium (mg/dL) | 9.7 ± 0.3 | 9.7 ± 0.5 | 9.7 ± 0.3 |
| Blood Pressure | |||
| Systolic (mmHg) | 129 ± 11 | 120 ± 12* | 123 ± 11 |
| Diastolic (mmHg) | 77 ± 7 | 77 ± 8 | 78 ± 8 |
| Anthropometrics | |||
| Weight (kg) | 71.3 ± 12.4 | 71.1 ± 12.1 | 71.3 ± 12.3 |
| BMI (kg/m2) | 24.9 ± 5.1 | 24.8 ± 5.0 | 24.9 ± 5.1 |
*
p ≤ 0.05 compared to baseline.
**
p ≤ 0.01 compared to baseline.
***
p 0.001 compared to baseline.
a
Values are means ± SDs. ADPKD, autosomal dominant polycystic kidney disease; BMI, body mass index; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate.