Table 2.
Variable | Placebo
|
Topiramate
|
||||
---|---|---|---|---|---|---|
Full | Completers | Attriters | Full | Completers | Attriters | |
N | 26 (39.4) | 20 (76.9) | 6 (23.1) | 40 (60.6) | 19 (47.5) | 21 (52.5) |
Age | 18.81 ± 2.08* | 18.70 ± 2.27 | 19.17 ± 1.33 | 20.30 ± 2.03* | 20.16 ± 2.27 | 20.43 ± 1.83 |
Male | 12 (46.2) | 9 (45.0) | 3 (50.0) | 20 (50.0) | 9 (47.4) | 11 (52.4) |
Minority | 13 (50.0) | 9 (45.0) | 4 (66.7) | 19 (47.5) | 12 (63.2) | 7 (33.3) |
Overall IQ | 96.85 ± 13.60 | 98.15 ± 13.12 | 92.50 ± 15.53 | 102.80 ± 17.18 | 97.84 ± 15.07 | 107.29 ± 18.08 |
BDI score | 6.08 ± 8.50 | 5.25 ± 6.54 | 8.83 ± 13.69 | 4.55 ± 5.08 | 5.68 ± 5.23 | 3.52 ± 4.83 |
Baseline cannabis problems | 25.46 ± 23.30 | 20.05 ± 13.64 | 43.50 ± 38.73 | 20.08 ±16.86 | 24.74 ± 20.07 | 15.86 ± 12.35 |
Baseline percent use days | 70.94 ± 28.60 | 66.78 ± 30.00 | 84.81 ± 19.02 | 70.22 ± 26.89 | 70.29 ± 27.11 | 70.16 ± 27.46 |
Baseline grams per use day | 0.88 ± 0.73 | 0.86 ± 0.69 | 0.93 ± 0.91 | 0.53 ± 0.37 | 0.62 ± 0.46 | 0.45 ± 0.25 |
Note. BDI = Beck Depression Inventory. All variables were measured at baseline. Tabled values for categorical variables are count (%), whereas values for continuous variables are mean ± standard deviation. Differences in categorical variables were calculated via chi-square tests, whereas differences in continuous variables were calculated via independent sample t-tests. Significant column differences based on bias-corrected 95% confidence intervals with 1000 bootstrap draws and noted by superscript letters.
Mdifference = − 1.49, t(64) = −2.89, p = .005, SE = .52, 95%CI [− 2.52, − 0.46]