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(A) Time course of mean and SD of the nonlinearity index defined as the relative change in modulus between 36 and 15% strain, normalized to unity at time 0 during 60 min in the tissue bath with or without adding bacterial collagenase. (B) Comparison of the percent increase in the normalized nonlinearity index from time 0 to 60 min. For the definition of the groups see the caption in Figure 3. The D0% group was statistically different from both the D40% and D80% groups.
