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. 2016 Jul 12;7:1088. doi: 10.3389/fmicb.2016.01088

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Copyright © 2016 Crozier, Hedley, Morris, Wagstaff, Andrews, Toth, Jackson and Holden.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flagella-curli regulatory network gene expression profiles. Expression data for selected E. coli O157:H7 (Sakai) genes in response to different plant extracts was overlaid onto the network to generate a color code of expression: orange for induction, blue for repression, and white for no change < ± twofold. Expression is provided for selected genes that were affected in at least one of the four plant extracts. Gene names are in italics; genes associated with a phenotype are grouped together; an overall approximate change (indicated by ‘∼’) is provided for flagella genes (data in Supplementary Table S2B). The data for all four conditions is arranged in a grid, ordered as indicated in the Key: LL, leaf lysates and RE, root exudates for spinach; Spin_PS, spinach CWPSs; Lett_PS, lettuce CWPSs. Regulatory connections, both direct and indirect (Pesavento et al., 2008; Pesavento and Hengge, 2012; Guttenplan and Kearns, 2013), with either positive (black arrow) or inhibitory (red bar) effects are shown.