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. 2016 Jul 12;7:202. doi: 10.3389/fphar.2016.00202

Table 1.

Interleukin 6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α) serum levels and IL-6, TNF-α, TLR-1, and TLR-3 mRNA expression of rats subchronically treated with OAO-ASA (8).

Groupn Serum concentration (pg/ml) mRNA expression (%)


IL-6 TNF-α IL-6 TNF-α TLR-1 TLR-3
Control 55.4 ± 1.6 1494 ± 332 100 ± 15 100 ± 7 100 ± 10 100 ± 13
OAO-ASA (8) 9.3 ± 0.8∗∗ 1099 ± 201 60 ± 5∗∗ 11 ± 29∗∗ 138 ± 13∗∗ 108 ± 19

TLR-1, TLR-3 = Toll-like receptor 1, Toll-like receptor 3, values are means ± SEM, n = number of animals: 10, = values expressed as a ratio: the gene/GAPDH, control = rats treated with 5% Tween 80, OAO-ASA (8) = rats treated with OAO-ASA (8) (dissolved in 5% Tween 80) in the dose of 30 mg/kg (p.o.) for 4 weeks, ∗∗ = vs. control, p < 0.05.