Table 5.

Steady-state trough levels^a maintained during IGHy treatment (excluding ramp-up) by infusion interval and by age group (<18, ≥18 years)

		IgG trough level (mg/dL)
Age groupb(years)	Infusion interval (weeks)	Number of subjects	Median	95 % CI for median
<18	2	2	1660	NA
	3	4	1094	914 to 1520
	4	18	1009	852 to 1200
≥18	2	16	1070	939 to 1330
	3	10	1195	944 to 1580
	4	48	976	935 to 1080
Total	2	18	1135	939 to 1440
	3	14	1195	958 to 1530
	4	66	983	946 to 1070

^a An IgG trough level qualifies as steady-state trough level if : for a 4-week infusion interval, the last two infusions; for a 3-week infusion interval, the last three infusions; and for a 2-week infusion interval, the last four infusions were no more than 2 days off the planned infusion date. If more than one IgG trough level qualified, the latest (per infusion interval) was taken

^bAge at screening in pivotal study