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Frequency of adverse cardiovascular events at follow-up between patients not taking thyroid replacement therapy and those taking thyroid replacement therapy with and without adequate replacement. Unadjusted Kaplan–Meier curves during 10-year follow-up for ( A ) major adverse cardiovascular and cerebral events, ( B ) cardiac death, ( C ) myocardial infarction, ( D ) heart failure, ( E ) target-vessel revascularization, and ( F ) stroke.
