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. 2016 Jun 24;36(5):405–412. doi: 10.3343/alm.2016.36.5.405

Table 3. Sensitivity and specificity for AMI with 95% CI for each assay at the enrollment time point.

Performance of AMI detection in a population with detectable TnI (for each assay)
Triage TnI (n=968) PathFast TnI (n = 989) Singulex TnI (n = 288)
Sensitivity (95% CI) 79.3 (70.5, 86.4) 76.7 (76.4, 84.5) 92.0 (83.4, 97.0)
Specificity (95% CI) 91.1 (89.0, 92.9) 92.8 (90.9, 94.4) 89.7 (84.8, 93.4)
C-Statistics (95% CI) 0.90 (0.86, 0.93) 0.88 (0.84, 0.92) 0.96 (0.93, 0.99)
Triage vs Singulex PathFast vs Singulex Triage vs PathFast
Comparison P = 0.0002, n = 74 P < 0.0001, n = 65 P = 0.1770, n = 130

Positive defined as ≥20, 29, and 10.2 pg/mL for Triage, PathFast, and Singulex, respectively.

Abbreviations: AMI, acute myocardial infarction; TnI, troponin; CI, confidence interval.